CH Paimpol, France

This 12.5 week fetus has a nuchal lucency

and a possible atrioventricular canal

A chorionic villus biopsy confirmed the diagnosis of Trisomy 21, and at autopsy at 14 week, the atrioventricular canal is confirmed.

The fetus has normal nasal bones (no hypoplasia) and 11 pairs of ribs.