OEIS complex

Tharinee Lumluk, MD., Nattinee Srisantiroj, MD. , Prapon Jaruyawong MD

Department of Obstetric and Gynecology, Rajavithi hospital, Bangkok,Thailand.

Case report 

This is a case of a healthy 27-year-old G1 P0 who was presented to our department at 23 weeks of gestation. She had non-contributive family or personal history. She was referred from another center for a suspicion of spina bifida.

Our ultrasound examination revealed the following findings:

  • Myelomeningocele
  • Bladder exstrophy
  • Omphalocele
  • Club feet

Our differential diagnosis included Omphalocele-Exstrophy-Imperforate anus-Spinal defects, OEIS complex. Patient decided for the pregnancy termination. Autopsy examination confirmed our ultrasound findings and described anal atresia as well.

Images 1,2: Image 1 shows an axial view, note the "banana" sign and abnormal appearance of the posterior fossa. Image 2 shows a mass protruding form the abdominal wall, located between the legs of the fetus.


Images 3,4: Image 3 shows insertion of the umbilical cord to the mass, which indicates omphalocele. Image 4 shows the mass between the legs, note the absence of the urinary bladder on all the images.


Images 5,6: Images of the abdominal mass, urinary bladder can not be seen. There is a normal amount of the amniotic fluid.


Images 7: Doppler of the umbilical artery.


Images 8,9: Fetus after pregnancy termination, note the myelomeningocele.


Images 10,11: Omphalocele, bladder exstrophy and anal atresia.


Discussion Board

Start a discussion about this article
Add bookmark Bookmarked