The department of Obstetrics and Gynecology, Hôpital Félix Guyon, rue des Topazes, 97400 Saint-Denis,

This is a case of a 20-year-old primigravida in whom a diagnosis of a septated fetal cystic hygroma with associated subcutaneous edema was made at 13 week After extensive counselling, the patient underwent a choriocentesis at 13 weeks that revealed a 45,X0 fetal karyotype.