Holoprosencephaly

Lenin Montilla, MD

Merida, Venezuela

This is a 29-year-old woman, G2P1,Ā at 16 weeksĀ and 6 days of gestation. TheĀ scanĀ revealed a fetus with alobar holoprosencephaly. It shows the following features:

  • Single ventricle
  • Absence of midline structures
  • Fused thalami

1

The dissection: the skull...

2

5

The brain (the "pancake" form)

3

Opening of the single ventricle:

4

Ā 

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