Obstetrical and gynecological department, San Bassiano Hospital, Bassano del Grappa, Italy.

The images and video below show a case of alobar holoprosencephaly diagnosed at 11 weeks of pregnancy. A chorionic villus sampling revealed normal karyotype (46, XX). The pregnancy was terminated.

Images 1 and 2: 11 weeks of pregnancy. The image 1 shows a transverse scan of the fetal head with holoprosencephaly. The image 2 shows a sagittal scan of the fetal head with alobar holoprosencephaly.

Video 1: 11 weeks of pregnancy. The video shows a transverse scan of the fetal head with alobar holoprosencephaly.