A 30 year old woman was refered for a second opinion at 25-week gestation. The following images were obtained at that time.

The fetal head (2D and 3D reconstructions) showed moderate hydrocephalus probably due to compression of foramen magnum.

The following coronal plane 3D reconstructions show the typical Kleeblattschädel or Cloverleaf skull.

Transverse mid face plane clearly show exophtalmos, and the facial profile show frontal bossing and low nasal bridge.

Further 3D surface rendering mode images show further details:

Note the "bell-shaped"  thorax seen on the images below.

The upper limbs were short, mostly rhizomelic and mantained a right angle throughout all examinations.

Lower limbs were as well very short and rhizomelic. The femurs in these next images show the typical "telephone receiver" shape.

Probably the most striking feature this fetus showed during its examination was the cloverleaf skull. In OMIM, entering only the key word "Cloverleaf skull" brings us to all differentials which are:

#187601   THANATOPHORIC DYSPLASIA WITH KLEEBLATTSCHAEDEL
607161     MULTIPLE CONGENITAL ANOMALIES SYNDROME WITH CLOVERLEAF SKULL
148800     KLEEBLATTSCHAEDEL SYNDROME
156830     MICROMELIC BONE DYSPLASIA WITH CLOVERLEAF SKULL
#187600  THANATOPHORIC DYSPLASIA; TD
#101600  PFEIFFER SYNDROME
#123790  CUTIS GYRATA SYNDROME OF BEARE AND STEVENSON
#182212  SHPRINTZEN-GOLDBERG CRANIOSYNOSTOSIS SYNDROME
*211890  CAMPOMELIA, CUMMING TYPE
211990    CAMPTOMELIC SYNDROME, LONG-LIMB TYPE
602361    GRACILE BONE DYSPLASIA
#604757  CRANIOSYNOSTOSIS, TYPE 2; CRS

Within these, the most probable one is Thanatophoric dysplasia (type II) with cloverleaf skull.

These are postmortem images of this fetus:

And the radiology.