Case report

20-year-old (G1P0) patient was referred to our ultrasound center al 24 weeks ^{4 days} of pregnancy due to suspicion of the skeletal dysplasia. Both parents had negative personal nor family history. Pregnancy was otherwise uncomplicated.
Our ultrasound examination revealed the following findings

- Long bones below 5^th percentile;
- Multiple fractures;
- Long bones were curved and bowed;
- Hypomineralization and softening of the fetal skull;

Based on the ultrasound findings the proposed diagnosis was Osteogenesis Imperfecta, type II.

The fetus was born at 36 weeks by C-Section and died 6 hours after birth.

Postnatal X-ray, pathological and genetic examination confirmed the prenatal findings and the diagnosis.

Images 1-6: 2D and 3D images showing hypomineralization of the fetal skull which was compressible during the examination, short and bowed long bones and multiples fractures.

Videos 1-4: 2D images showing hypomineralization of the fetal skull which was compressible during the examination, short and bowed long bones and multiples fractures.