A bicuspid aortic valve is most commonly a congenital condition of the aortic valve where two of the aortic valvular leaflets fuse during development resulting in a valve that is bicuspid instead of the normal tricuspid configuration.
Bicuspid aortic valves are the most common cardiac valvular anomaly, occurring in 1- 2% of the general population. it is twice as common in males as in females.
Bicuspid aortic valve is an inheritable condition, the incidence of bicuspid aortic valve can be as high as 10% in families affected with the valve problem.
Figure 1: The sketch of the bicuspid aortic valve and text of Leonardo da Vinci. In the text, da Vinci describes the optimal geometric properties of the tricuspid aortic valve in comparison to a quadricuspid valve.