Medical Genetic Center, Gomel, Belarus.
The following images shows some prenatal images of a fetus which turned out to be the Walker-Warburg syndrome. The mother was 21-year-old, G1P0. The first trimester examination at 13 weeks found the NT 1,3 mm, nasal bone length 2,3 mm. At 21st week we found ventriculomegaly of the lateral cerebral ventricles (13 mm), hypoplasia of the cerebellar vermis, posterior fossa cyst (Dandy-Walker complex), and agyria. The findings were confirmed at 30 and 35 weeks and an abnormal fetal profile with hypotelorism were also noted. The neonate was delivered at 39 weeks (3000 g, 50 cm). Postnatally the baby showed myoclonic convulsions, muscular dystrophy and the diagnosis of the Walker-Warburg syndrome was confirmed.
Images 1, 2: 21 weeks. The image 1 shows a transverse scan of the fetal head with the dilation of the lateral cerebral ventricles. The image 2 shows the fetal profile.