Agenesis of the corpus callosum

Fabrice Cuillier, MD*; L. Lagarde, MD**

*Ā  Department of Gynecology, Felix Guyon Hospital, 97400 Saint- Denis, Ile de la Reunion, France; tel: 0262 90 55 22; fax : 0262 90 77 30;
** Department of Gynecology, Gabriel Martinā€™Hospital, 97400 Saint-Denis, Ile de la RĆ©union.

Case report

A 35-year-old G5P4, referred to our antenatal unit at 35 weeks. HerĀ first trimester screening was normal. The second trimester ultrasoundĀ wasn"t practiced. Our investigation revealed bilateral ventriculomegaly (14 mm) with agenesis of the corpus callosum. The pericallosal artery could not be identified andĀ the MRIĀ confirmed the diagnosis. No associated anomalies were seen and the karyotype and serological tests (Toxoplasmosis, Rubeola, CMV, Herpes, and Chikungunya) were also normal. The patient delivered at 37 weeks of pregnancy and the diagnosis was confirmed.

Images 1, 2: Transverse images of the fetal head showing ventriculomegaly with characteristic "tear drop" configuration of the lateral ventricles.

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Images 3, 4: Sagittal color Doppler images were not able to detect theĀ pericallosal artery.

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Images 5, 6: MRI images showing dilated lateral cerebral ventricles and absence of the corpus callosum.

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